IEM 1754 2HBr
CAS No. 162831-31-4
IEM 1754 2HBr( IEM-1754 dihydrobromide | IEM 1754 dihydrobromide )
Catalog No. M17347 CAS No. 162831-31-4
IEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
2MG | 29 | Get Quote |
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5MG | 43 | Get Quote |
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10MG | 67 | Get Quote |
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25MG | 147 | Get Quote |
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50MG | 239 | Get Quote |
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100MG | 356 | Get Quote |
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500MG | 1053 | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameIEM 1754 2HBr
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NoteResearch use only, not for human use.
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Brief DescriptionIEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
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DescriptionIEM-1754 2HBr is a voltage-dependent open-channel blocker of AMPA receptors. It acts by selectively blocking GluR2 subunit-lacking (Ca2+-permeable) receptors.
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In Vitro——
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In Vivo——
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SynonymsIEM-1754 dihydrobromide | IEM 1754 dihydrobromide
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptormGluR1| mGluR3
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number162831-31-4
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Formula Weight412.25
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Molecular FormulaC16H30N2·2HBr
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (242.57 mM)
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SMILESBr.Br.NCCCCCNCC12CC3CC(CC(C3)C1)C2
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Chemical NameN-(Tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1,5-pentanediamine dihydrobromide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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PBP 10
Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.
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Ombuoside
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Urechistachykinin II
Urechistachykinin II (Uru-TK II) is an invertebrate rapid kinin-related peptide (TRPs) isolated from carotenoid worms.